Once home to the mansions of the Big Four railroad barons, Nob Hill retains a sense of wealth and privilege. Some of the city’s swankiest hotels are here, as are the ornate, Gothic-style Grace Cathedral and charming Huntington Park. Steep streets are dotted with restaurants and nightspots like the Top of the Mark lounge, with its 360-degree views. The Cable Car Museum exhibits antique cars alongside live machinery. ― Google

Area: 200 acres

Area code: Area code 415

ZIP codes: 94108, 94109, 94133

Restaurants: Hotel Fairmont San Francisco, Nob Hill Cafe

Hotels: Hotel Fairmont San Francisco